AMD Unveils Powerful MI350X and MI355X AI GPUs, Challenging Nvidia's Dominance

21 Sources

AMD launches new MI350X and MI355X AI GPUs, claiming significant performance gains over previous generations and competitive edge against Nvidia's offerings. The company also previews future Instinct GPUs and rack-scale solutions.

AMD Unveils Powerful New AI GPUs

AMD has announced its latest AI-focused GPUs, the MI350X and MI355X, at its Advancing AI 2025 event in San Jose, California. These new accelerators represent a significant leap in performance, with AMD claiming up to a 4X increase in "AI compute performance" compared to prior-generation models 1.

Source: TweakTown

Source: TweakTown

Technical Specifications and Improvements

Both the MI350X and MI355X feature:

  • Up to 288GB of HBM3E memory
  • Up to 8 TB/s of memory bandwidth
  • Support for FP4 and FP6 data types
  • CDNA 4 architecture
  • TSMC's N3P process node for compute chiplets

The MI355X, designed for liquid-cooled systems, pushes the envelope with a 1,400W Total Board Power (TBP), while the MI350X is geared for air-cooled solutions with a lower TBP 1.

Performance Claims and Comparisons

Source: TweakTown

Source: TweakTown

AMD asserts that the MI355X can match and sometimes exceed Nvidia's B200, currently the most powerful data center GPU from Nvidia 5. The company claims:

  • 3X performance boost over the prior-gen MI300X
  • 35X increase in inference performance
  • Competitive or superior performance in lower-precision formats like FP16, FP8, and FP4 compared to Nvidia's offerings 1

Architectural Advancements

The new GPUs maintain the fundamental design principles of merging 3D and 2.packaging technology:

  • Eight XCD chiplets, each with 32 compute units (CU) enabled
  • Total of 256 CU
  • 185 billion transistors, a 21% increase over the prior generation
  • Improved Infinity Fabric bus width, enhancing bi-sectional bandwidth to up to 5.TB/s 1

Deployment and Scalability

The MI350X and MI355X come in an OAM form factor and are compatible with standardized UBB form factor servers. AMD supports various networking options, including:

  • Pollara Ultra Ethernet Consortium-capable NICs (UEC) for scale-out solutions
  • Ultra Accelerator Link (UAL) interconnect for scale-up networking 1

Future Roadmap: MI400X and Helios

Source: CRN

Source: CRN

AMD also previewed its upcoming MI400X GPU and Helios rack-scale system:

  • MI400X is projected to be 10 times more powerful than the MI300X
  • Helios will feature EPYC 'Venice' CPUs, MI400-series GPUs, and Pensando 'Vulcano' NICs
  • The system aims to deliver leadership compute density and memory bandwidth 2

Software Optimization and Performance Gains

A significant portion of the performance improvements comes from software optimizations:

  • AMD's ROCm software stack has delivered a 3x performance improvement in AI training
  • 3.5x improvement in AI inference on the same hardware 5

Market Availability and Future Prospects

The MI350X and MI355X are already shipping to customers, with broader availability from partners like Dell, HP Enterprise, Supermicro, Gigabyte, and ASRock Rack starting in the third quarter of 2025 5. As AMD continues to push the boundaries of AI GPU performance, the competition with Nvidia in the data center GPU market is set to intensify, potentially reshaping the landscape of AI computing infrastructure.)

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