Anthropic Claude Now Runs on NVIDIA GB300 Blackwell Ultra GPUs in Microsoft Azure

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Anthropic's Claude models are now generally available in Microsoft Foundry on Azure, powered by NVIDIA's GB300 Blackwell Ultra GPUs. This marks Anthropic's first NVIDIA deployment, giving Azure-native enterprises access to advanced computing power for building autonomous and domain-specific AI agents that can automate complex business tasks across multiple domains.

Anthropic Claude Launches on NVIDIA GB300 in Microsoft Azure

Anthropic's Claude models are now generally available in Microsoft Foundry, running on NVIDIA's Blackwell Ultra GB300 GPUs and hosted on Microsoft Azure

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. This deployment represents Anthropic's first NVIDIA deployment and gives Azure-native enterprises a powerful foundation for building autonomous and domain-specific AI agents

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. The Claude models on Microsoft Azure currently include Claude Opus 4.8 and Claude Haiku 4, with Anthropic stating it will continue to deploy and expand on the platform

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Source: NVIDIA

Source: NVIDIA

Advanced Infrastructure Powers Enterprise AI Adoption

With Claude in Foundry running on NVIDIA GB300 NVL72 systems with NVIDIA Quantum-X800 InfiniBand networking, enterprises can now build and run more powerful agentic systems, including autonomous and specialized sub-agents that work across business domains to perform advanced tasks

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. The deployment is designed to improve inference performance and efficiency while reducing the total cost of ownership for enterprise AI workloads

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. As agentic AI continues to drive enterprise innovation and becomes more autonomous, organizations need access to computing power to build and deploy specialized AI agents to accelerate essential business tasks

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Strategic Partnership Expands Developer Capabilities

NVIDIA is working with Anthropic to extend developer capabilities by integrating NVIDIA tools into the Anthropic stack

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. This integration enables enterprises to give Claude agents domain-specific abilities through NVIDIA-verified agent skills, enabled by access to NVIDIA accelerated computing

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. Enterprises can embed AI agents deeply into their business and use them as the operating system for the organization

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. The collaboration builds on the strategic partnership Microsoft, NVIDIA and Anthropic announced in November to expand enterprise access to Anthropic's Claude models and offer them on NVIDIA accelerated computing

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Secure Infrastructure for Autonomous Agents

Enterprises can run Claude agents on Azure using the NVIDIA Secure Agent Workspace Reference Design, which provides a blueprint for running autonomous agents in a governed environment where identity, network access, credentials and runtime policy are controlled at the infrastructure level

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. Microsoft Azure provides billing, authentication and governance controls for the deployment

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. This infrastructure-level approach to security matters as enterprises increase investment in agentic AI applications that automate complex business tasks

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. The deployment enables customers to deploy more advanced AI agents, including specialized sub-agents that can operate across different business functions

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