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Claude Meets Blackwell Ultra: Anthropic's Models Now Run on NVIDIA GB300 in Azure
Now generally available in Microsoft Foundry, Claude on NVIDIA GB300 Blackwell Ultra gives Azure-native enterprises a new foundation for building autonomous and domain-specific AI agents. Anthropic's Claude models in Microsoft Foundry -- hosted on Microsoft Azure and running on NVIDIA GB300 Blackwell Ultra GPUs -- are now generally available, giving Azure-native enterprises a powerful new way to build autonomous and domain-specific AI agents. As agentic AI continues to drive enterprise innovation and becomes more autonomous, organizations need access to computing power to build and deploy specialized agents to accelerate essential business tasks. And having great inference performance and efficiency reduces total cost of ownership and drives positive company results. With Claude in Foundry running on NVIDIA GB300 NVL72 systems with NVIDIA Quantum-X800 InfiniBand networking, enterprises can now build and run more powerful agentic systems, including autonomous and specialized sub-agents that can work across business domains to perform advanced tasks. A Growing Partnership NVIDIA is working with Anthropic to extend developer capabilities by integrating NVIDIA tools into the Anthropic stack. That integration enables enterprises to give Claude agents domain-specific abilities. Through NVIDIA verified agent skills, enabled by access to NVIDIA accelerated computing, enterprises can embed AI agents deeply into their business and use them as the operating system for the organization. Enterprises can run Claude agents on Azure by using the NVIDIA Secure Agent Workspace Reference Design. It provides a blueprint for running autonomous agents in a governed environment where identity, network access, credentials and runtime policy are controlled at the infrastructure level. Claude in Microsoft Foundry accelerated by NVIDIA GB300 GPUs on Azure builds on the strategic partnership Microsoft, NVIDIA and Anthropic announced in November to expand enterprise access to Claude and offer Anthropic models on NVIDIA accelerated computing. Get started by visiting Claude in Microsoft Foundry and learn more in Foundry documentation.
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Anthropic Claude launches on Microsoft Azure Foundry
Anthropic announced that its Claude AI models are now available in Microsoft Foundry on Azure, marking the first deployment on Nvidia hardware. The Claude models operate on Nvidia's GB300 Blackwell Ultra GPU systems, enabling Azure customers to develop autonomous and domain-specific AI agents. The deployment utilizes Nvidia GB300 NVL72 systems with Quantum-X800 InfiniBand networking. This setup is intended to enhance inference performance and efficiency while lowering total ownership costs for enterprise AI workloads. This announcement follows a statement from Nvidia and Microsoft in June, indicating that Claude models would soon "run natively" on Azure's Nvidia GB300 systems. The deployment aligns with growing enterprise interest in agentic AI applications. The launch builds on a strategic partnership established in November 2025, where Anthropic committed to purchase $30 billion in Azure compute capacity. Nvidia and Microsoft agreed to invest $10 billion and $5 billion in Anthropic, respectively. Initially, Anthropic's compute commitment was set to reach up to one gigawatt of capacity using Nvidia's Grace Blackwell and Vera Rubin systems. This partnership allowed for Claude's integration across Microsoft's Copilot family, which includes GitHub Copilot and Microsoft 365 Copilot. In October 2025, Microsoft deployed a large-scale Azure cluster featuring over 4,600 Nvidia GB300 Blackwell Ultra GPUs, initially designed for OpenAI's inference workloads. The cluster's advanced capabilities position Azure as a multi-model platform for enterprise customers, with Anthropic's Claude now the second major AI model family running on this infrastructure.
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NVIDIA's Blackwell Ultra GB300 Now Powers Anthropic's Claude Models on Microsoft Azure, Targeting Autonomous Enterprise Agents
Anthropic has announced the general availability of its Claude AI models on Microsoft Azure, powered by NVIDIA's Blackwell Ultra GPUs. Anthropic & NVIDIA Bring Claude AI Models to Microsoft Azure - Running on NVIDIA's Blackwell Ultra GB300 Platform As Agentic workloads continue to drive the AI segment, NVIDIA is working with leading firms to deliver faster and expanded capabilities to end-users. Today, NVIDIA partnered with Anthropic to deliver Claude models on Microsoft Azure. With the general availability of Anthropic's Claude models, Microsoft Azure provides billing, authentication, and governance controls. The two models that are available today are Claude Opus 4.8 and Claude Haiku 4. Anthropic states that it will continue to deploy and expand on Azure. Press Release: With Claude in Foundry running on NVIDIA GB300 NVL72 systems with NVIDIA Quantum-X800 InfiniBand networking, enterprises can now build and run more powerful agentic systems, including autonomous and specialized sub-agents that can work across business domains to perform advanced tasks. A Growing Partnership NVIDIA is working with Anthropic to extend developer capabilities by integrating NVIDIA tools into the Anthropic stack. That integration enables enterprises to give Claude agents domain-specific abilities. Through NVIDIA-verified agent skills, enabled by access to NVIDIA accelerated computing, enterprises can embed AI agents deeply into their business and use them as the operating system for the organization. Enterprises can run Claude agents on Azure by using the NVIDIA Secure Agent Workspace Reference Design. It provides a blueprint for running autonomous agents in a governed environment where identity, network access, credentials, and runtime policy are controlled at the infrastructure level. Claude in Microsoft Foundry, accelerated by NVIDIA GB300 GPUs on Azure, builds on the strategic partnership Microsoft, NVIDIA, and Anthropic announced in November to expand enterprise access to Claude and offer Anthropic models on NVIDIA accelerated computing. Follow Wccftech on Google to get more of our news coverage in your feeds.
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Anthropic's first NVIDIA deployment launched at Microsoft Azure By Investing.com
Investing.com -- Anthropic said on Monday its Claude family of artificial intelligence models is now available in Microsoft Foundry on Azure, running on NVIDIA's GB300 Blackwell Ultra GPU systems, marking the AI startup's first deployment on NVIDIA hardware. The availability gives Azure customers access to Claude models for building autonomous and domain-specific AI agents, as enterprises increase investment in agentic AI applications that automate complex business tasks. Anthropic said the deployment is designed to improve inference performance and efficiency while reducing the total cost of ownership for enterprise AI workloads. The launch builds on a strategic partnership announced by Microsoft, NVIDIA and Anthropic in November to expand enterprise access to Claude models through NVIDIA-accelerated computing. The models run on NVIDIA GB300 NVL72 systems with Quantum-X800 InfiniBand networking, enabling customers to deploy more advanced AI agents, including specialized sub-agents that can operate across different business functions. NVIDIA said it is also expanding its partnership with Anthropic by integrating its software tools into the Claude ecosystem. The collaboration includes NVIDIA Verified Agent Skills, allowing enterprises to equip Claude agents with domain-specific capabilities using NVIDIA-accelerated computing. Customers can deploy Claude agents on Azure using NVIDIA's Secure Agent Workspace Reference Design, which provides infrastructure-level controls for identity, networking, credentials and runtime policies.
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Anthropic's Claude AI models are now generally available in Microsoft Foundry on Azure, powered by NVIDIA GB300 Blackwell Ultra GPUs. This marks Anthropic's first NVIDIA deployment, enabling Azure customers to build autonomous and domain-specific AI agents with enhanced inference performance and reduced costs.
Anthropic has launched its Claude AI models on Microsoft Azure, marking Anthropic's first NVIDIA deployment and a significant expansion of enterprise access to advanced AI capabilities. The Claude AI models on Microsoft Azure are now generally available in Microsoft Foundry, running on NVIDIA GB300 Blackwell Ultra GPUs
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. This deployment gives Azure-native enterprises a powerful foundation for building autonomous enterprise agents and domain-specific AI agents that can accelerate essential business tasks across multiple domains.
Source: NVIDIA
The models currently available include Claude Opus 4.8 and Claude Haiku 4, with Anthropic committing to continue expanding its presence on the platform
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. Azure customers now gain access to these models with integrated billing, authentication, and governance controls through Microsoft Foundry3
.The deployment leverages NVIDIA GB300 NVL72 systems paired with Quantum-X800 InfiniBand networking, a configuration designed to deliver superior inference performance and efficiency while reducing total cost of ownership for enterprise AI workloads
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4
. This infrastructure enables enterprises to build and run more powerful agentic AI systems, including specialized sub-agents that can operate across different business functions to perform advanced tasks1
.The timing aligns with Microsoft's October 2025 deployment of a large-scale Azure cluster featuring over 4,600 NVIDIA GB300 Blackwell Ultra GPUs, initially designed for OpenAI's inference workloads
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. With Anthropic Claude now running on this infrastructure, Azure positions itself as a multi-model platform capable of serving diverse enterprise customers with different AI model preferences2
.This launch builds on a strategic partnership announced in November 2025, where Anthropic committed to purchase $30 billion in Azure compute capacity
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. As part of this arrangement, NVIDIA and Microsoft Azure agreed to invest $10 billion and $5 billion in Anthropic, respectively2
. The compute commitment was initially set to reach up to one gigawatt of capacity using NVIDIA's Grace Blackwell and Vera Rubin systems2
.NVIDIA is now working with Anthropic to extend developer capabilities by integrating NVIDIA tools into the Anthropic stack, enabling enterprises to give Claude agents domain-specific abilities
1
. Through NVIDIA-verified agent skills and access to accelerated computing, enterprises can embed AI agents deeply into their business operations and use them as the operating system for the organization3
.Related Stories
Enterprises can run Claude agents on Azure using the NVIDIA Secure Agent Workspace Reference Design, which provides a blueprint for running autonomous agents in a governed environment
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. This framework ensures that identity, network access, credentials, and runtime policy are controlled at the infrastructure level, addressing critical security and compliance requirements for enterprise deployments3
.As agentic AI continues to drive enterprise innovation and becomes more autonomous, organizations require access to substantial computing power to build and deploy specialized agents that can accelerate business tasks
1
. The combination of Claude's capabilities with NVIDIA's hardware and Microsoft's cloud infrastructure creates a comprehensive solution for enterprises looking to implement advanced AI systems that can work across business domains and perform complex, multi-step operations with minimal human intervention.Summarized by
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