Pathos AI Raises $237M, Partners with Bristol Myers Squibb and Tempus AI for Neuroscience Push

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Pathos AI secured $237 million in Series E funding at a $3 billion valuation, led by Bristol Myers Squibb. The company is expanding beyond oncology into neuroscience drug development through strategic partnerships with Bristol Myers Squibb and Tempus AI, focusing on Alzheimer's disease research using its AI-driven Foundry platform.

Pathos AI Secures Major Funding and Strategic Partnerships

Pathos AI closed a $237 million Series E funding round at a $3 billion valuation, with Bristol Myers Squibb leading the investment

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. The deal marks a significant expansion for the New York-based biotech company, which has attracted backing from pharmaceutical giants including AstraZeneca, NEA, and General Atlantic

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. Bristol Myers Squibb gains non-exclusive strategic access to the Pathos Foundry platform across its broader portfolio, along with three-year exclusive rights to use the platform for its neuroscience development programs

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Source: ET

Source: ET

Strategic Pivot into Neuroscience Drug Development

The partnerships represent Pathos AI's first major move beyond oncology, placing Alzheimer's disease at the center of its new neuroscience strategy

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. The company will combine its agentic AI platform with Tempus AI's large-scale clinical datasets and Bristol Myers Squibb's neuroscience expertise to accelerate drug development for neurological disorders

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. This collaboration aims to support the design of adaptive clinical trials for Alzheimer's disease and related conditions, leveraging AI-driven research to improve understanding of disease progression and treatment outcomes

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Data Licensing Agreements Worth $192.5 Million

Pathos AI commissioned Tempus AI to build a comprehensive dataset covering hundreds of thousands of patients with neurological conditions under a five-year, $55 million agreement

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. Tempus will deliver up to 500,000 de-identified records of patients with Alzheimer's disease or other neurological disorders at a rate of 100,000 records per year, with payments consisting of $50 million in data license fees and $5 million for record updates

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. The broader data licensing agreements between Tempus AI, Bristol Myers Squibb, and Pathos AI will provide Tempus with aggregate cash payments of up to $192.5 million over approximately five years

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Pathos Foundry Platform Powers AI Drug Development

The Pathos Foundry platform has access to approximately 200 petabytes of oncological data and uses AI agents to pinpoint the most promising drug candidates from hundreds of potential molecules

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. According to Pathos CEO Iker Huerga, "Foundry has fundamentally accelerated our ability to identify highly promising clinical assets and integrate them into our pipeline"

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. The platform analyzes real-world multimodal datasets to help researchers identify patients who could benefit most from each therapy and plan biomarker-driven clinical trials

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Source: SiliconANGLE

Source: SiliconANGLE

Oncology Pipeline and Cancer Drug Development

Pathos AI stated that its key priority remains its JSKN016 program, which aims to develop a cancer therapy based on an antibody-drug conjugate

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. Antibody-drug conjugates are upgraded antibodies containing an antigen with therapeutic properties that attach to cancer cells and cause them to absorb the molecule, which neutralizes them

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. The company will use Series E funding to finance three other drug programs, including a collaboration with AstraZeneca to develop an ER PROTAC drug that harnesses cells' built-in material recycling mechanism to treat cancer

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Source: Market Screener

Source: Market Screener

Tempus Expands Oncology Data Access for Bristol Myers Squibb

Bristol Myers Squibb significantly expanded its strategic relationship with Tempus AI through a multi-year agreement running through 2031, under which BMS will license multimodal oncology data to support biological and clinical insight identification, novel drug target discovery, and therapeutic development across its oncology portfolio

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. BMS will pay fixed payments totaling $137.5 million, invoiced quarterly, and gain access to Tempus Lens Platform, an AI-first, agentic platform for oncology drug development built on one of the world's largest real-world multimodal datasets

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. With this agreement, BMS becomes one of Tempus's largest licensors of de-identified oncology data

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