An AI read 16 years of heart records. Its maker says it hasn't been shown to help yet

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Dyania Health and NVIDIA announced a collaboration to run the Synapsis AI clinical reasoning engine on hospital-owned infrastructure, keeping patient records in-house. Its first study, with Cleveland Clinic, predicts heart valve failure risk across 7,812 patients.

Dyania Health and Nvidia announced a collaboration on Nov. 13 to run Dyania's Synapsis AI clinical reasoning engine on hospital-owned Nvidia infrastructure, at the scale of a health system's entire patient population

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. The companies say the goal is to let a health system learn from the full histories of patients it has already treated

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. That, they say, points to earlier identification of care needs

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Synapsis reads the whole chart, covering written clinical records, imaging and pathology findings and lab results

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. Its answers come with evidence traceable to their source in the chart

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. Clinicians review the output and make every decision

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. It runs on Nvidia accelerated computing inside the hospital's firewall, so records are processed onsite and, the companies say, never leave

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. The stack is Nvidia's end to end: Dyania trains its models with Nvidia NeMo and optimizes them with TensorRT

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Source: NVIDIA

Source: NVIDIA

Much of what matters clinically sits in narrative notes that resist analysis at scale, which has made manual chart review a bottleneck for registries and outcomes studies

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. The field is crowded, too. Google Cloud launched Gemini for healthcare the same week, and Bunkerhill raised $55 million for hospital AI agents

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. Proven gains for patients remain hard to find across hospital AI, and doctors have objected when claims run ahead of proof

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The valve study

The collaboration's first work is a Cleveland Clinic study of 7,812 people given aortic valve replacements between 2005 and 2021, covering up to 16 years of follow-up care

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. Most of that follow-up record sits in narrative text and ultrasound readings that registries struggle to capture

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. Synapsis answered 88 clinical questions per patient, covering valve characteristics, co-existing conditions, lab trends, medications and later clinical events

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. From those answers it built a model of valve failure and reintervention risk at three, five and ten years after surgery

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In the model's findings, the kind of valve implanted mattered most for how quickly it deteriorated, and each follow-up ultrasound sharpens its outlook

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. Nvidia said the same chart review done by hand would have taken clinicians years

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. The study was built around the question valve patients actually ask: how long will my replacement valve last, and will I need another operation

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What the first study shows

In Schlosser's telling, the collaboration is a watershed moment: for the first time, she says, a health system can reason across every patient's full record at once rather than one chart at a time

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. Dyania says the same approach could extend to finding clinical-trial-eligible patients, closing care gaps in heart and cancer care, and filling registries

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. The companies also plan joint case studies and are evaluating Nvidia's Confidential Computing and Blackwell Ultra GPUs for near-real-time clinical insight

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The study demonstrates that the tool can assemble a dataset and forecast risk

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. Whether patients actually do better is untested

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. Cleveland Clinic, the study site, is also an investor in Dyania, an interest it disclosed last year

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. Outside validation, Dyania says, is still to come

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Source: News-Medical

Source: News-Medical

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