6 Sources
[1]
Microsoft deploys world's first 'supercomputer-scale' GB300 NVL72 Azure cluster -- 4,608 GB300 GPUs linked together to form a single, unified accelerator capable of 1.44 PFLOPS of inference
Microsoft has just upgraded its Azure cloud platform with Nvidia's Blackwell Ultra, deploying what it calls the world's first large-scale GB300 NVL72 supercomputing cluster. This cluster includes several racks housing exactly 4,608 GB300 GPUs connected by NVLink 5 switch fabric, which is then
[2]
Microsoft Azure Unveils World's First NVIDIA GB300 NVL72 Supercomputing Cluster for OpenAI
New state-of-the-art platform enables next-generation AI model development and deployment while furthering American leadership in AI. Microsoft Azure today announced the new NDv6 GB300 VM series, delivering the industry's first supercomputing-scale production cluster of NVIDIA GB300 NVL72 systems,
[3]
Microsoft Azure upgraded to NVIDIA GB300 'Blackwell Ultra' with 4600 GPUs connected together
TL;DR: Microsoft has deployed its first large-scale Azure cluster featuring over 4,600 NVIDIA GB300 "Blackwell Ultra" GPUs, enabling AI model training from months to weeks. This high-performance system supports multitrillion-parameter models with advanced NVLink bandwidth and InfiniBand
[4]
Microsoft Azure Debuts Nvidia GB300 Cluster for OpenAI AI Workloads
Microsoft has procured a total of 72 Nvidia Blackwell Ultra GPUs Microsoft Azure unveiled the new NDv6 GB300 virtual machine (VM) series on Thursday. Claimed to be the industry's first supercomputing-scale production cluster of the Nvidia GB300 NVL72 systems, it will be made available for OpenAI's
[5]
Microsoft Azure Gets An Ultra Upgrade With NVIDIA's GB300 "Blackwell Ultra" GPUs, 4600 GPUs Connected Together To Run Over Trillion Parameter AI Models
NVIDIA GB300 "Blackwell Ultra" Crunches Through 100s of Trillions of Parameters AI Models Within Microsoft's latest Azure Platform Microsoft's Azure has received the Blackwell Ultra upgrade. The latest large-scale and production cluster has been integrated with over 4,600 GPUs based on NVIDIA's
[6]
Microsoft Azure deploys world's first NVIDIA GB300 NVL72 supercomputer for OpenAI
Microsoft announces on Azure the launch of the world's first cluster using the NVIDIA GB300 NVL72 system, designed for OpenAI's artificial intelligence applications. This platform brings together more than 4,600 NVIDIA Blackwell Ultra graphics processors, interconnected via the InfiniBand
Share
Copy Link
Microsoft has deployed a groundbreaking supercomputer-scale cluster of NVIDIA GB300 NVL72 systems on its Azure platform, featuring over 4,600 Blackwell Ultra GPUs. This state-of-the-art infrastructure aims to accelerate AI model training and inference for OpenAI's most demanding workloads.
Microsoft has unveiled a revolutionary upgrade to its Azure cloud platform, deploying the world's first large-scale NVIDIA GB300 NVL72 supercomputing cluster
1
2
. This cutting-edge infrastructure, featuring over 4,600 NVIDIA Blackwell Ultra GPUs, is set to redefine the landscape of AI model training and inference3
.
Source: Gadgets 360
The new Azure NDv6 GB300 VM series boasts impressive specifications:
3
3
2
2
3
This powerful configuration allows the cluster to function as a single, unified accelerator, capable of handling massive AI workloads with unprecedented efficiency
1
.
Source: NVIDIA
Microsoft claims that this new infrastructure can dramatically reduce AI model training times from months to weeks
3
. The cluster is optimized for reasoning models, agentic AI systems, and multimodal generative AI workloads, supporting the training of models with hundreds of trillions of parameters4
.The deployment of this cluster is the result of a deep partnership between NVIDIA and Microsoft, aimed at building AI infrastructure for the world's most demanding workloads
2
. It's particularly noteworthy that this cluster will be dedicated to OpenAI workloads, furthering the collaboration between these tech giants1
.To achieve this level of performance, Microsoft had to reimagine every layer of its data center
2
. Key innovations include:1
5
4
Related Stories
This deployment marks a significant milestone in the advancement of AI infrastructure. Ian Buck, VP of Hyperscale and High-performance Computing at NVIDIA, stated that this system "sets the definitive new standard for accelerated computing"
3
. As Microsoft aims to scale to hundreds of thousands of NVIDIA Blackwell Ultra GPUs globally, it's poised to unlock new frontiers in AI research and development5
.The introduction of Microsoft's NVIDIA GB300 NVL72 supercomputing cluster represents a leap forward in AI infrastructure. As this technology scales and evolves, it promises to accelerate AI innovation across various sectors, potentially leading to breakthroughs in fields ranging from scientific research to commercial applications.
Summarized by
Navi
[2]
[3]
1
Technology

2
Policy and Regulation

3
Technology
